And men should know that from nothing else but from the brain come joy, laughter, jests, and sorrows, griefs, despondency and lamentations. And by this… we acquire wisdom and knowledge, and we see and hear and know what are foul and what are fair, what sweet and what unsavory… and by the same organ we become mad and delirious and fears andĀ terrorsĀ assail us.
— Hippocrates 460-377BC